Spontaneous coronary artery dissection in polycystic kidney disease

Farah Klingenberg-Salachova1, Sander Limburg2, Frans Boereboom1

  • 1Department of General Medicine, Diakonessenhuis, Utrecht, The Netherlands.

Insights

Autosomal-dominant polycystic kidney disease (ADPKD) may cause unstable arteries, increasing coronary artery dissection (CAD) risk. Early chest pain in ADPKD patients warrants further investigation for missed CAD.

Area of Science:

  • Cardiology
  • Nephrology
  • Genetics

Background:

  • Autosomal-dominant polycystic kidney disease (ADPKD) is a genetic disorder affecting the kidneys.
  • The association between ADPKD and coronary artery dissection (CAD) is not well-established.
  • Vascular abnormalities in ADPKD may predispose individuals to arterial events.

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