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Updated: Apr 10, 2026

The Extraction of Liver Glycogen Molecules for Glycogen Structure Determination
Published on: February 8, 2022
AA Amyloidosis in a patient with glycogen storage disorder and progressive chronic kidney disease
Jonathan Dick1, Nicola Kumar2, Catherine Horsfield3
1Renal Unit , King's College Hospital NHS Foundation Trust , Denmark Hill, London , UK.
Abstract:
Type 1 glycogen storage diseases (GSD) are inherited metabolic diseases caused by defects in the activity of the glucose-6-phosphate transporter. We present the case of a 40-year-old male with glycogen storage disease type 1b (GSD1b) who was referred to our nephrology service for evaluation of his chronic kidney disease and found to have AA amyloid deposition on renal biopsy. Amyloid is a described complication of GSD1b. As the treatment of GSD has improved, patients are surviving longer and are now presenting more frequently to adult services. It is important that clinicians are aware of the possible renal complications of GSD1b.
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