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[New therapeutical options for heavy gastrointestinal bleeding]

Georg Braun1, Helmut Messmann1

  • 1III. Medizinische Klinik, Klinikum Augsburg.

Deutsche Medizinische Wochenschrift (1946)
|June 13, 2015
PubMed

The number of patients taking new oral anticoagulants is rising, so is the number of serious bleeding events. In severe bleeding, the decision to start a procoagulant therapy is difficult to take. With Idarucizumab and Andexanet Alfa, specific antidotes have been developed against both, direct thrombin inhibitors as well as direct Factor Xa inhibitors. In the endoscopic treatment of severe gastrointestinal bleeding, alternative treatment options are available with Hemospray™, Endoclot™ and new hemostasis clips. Especially in the recurrent ulcer bleeding, the newly developed clips can achieve hemostasis and prevent an operational procedure.

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