Related Experiment Video
Updated: Apr 10, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Interactions between childhood maltreatment and brain-derived neurotrophic factor and serotonin transporter
Kate L Harkness1, John Strauss2, R Michael Bagby3
1Queen׳s University, Department of Psychology, Kingston, ON, Canada.
Abstract:
This study represents the first replication of the BDNF Val66Met ⁎ 5-HTTLPR ⁎ childhood maltreatment effect on self-reported depression symptoms using a rigorous maltreatment interview. Participants included a community sample of 339 adolescents/young adults (age 12-33; 265 female). In the context of childhood neglect, among BDNF Met-carriers, s-allele carriers of 5-HTTLPR reported significantly higher depression than l/l homozygotes, whereas a differential relation of 5-HTTLPR genotype to depression was not seen among BDNF Val/Val homozygotes.
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