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Changing relationship among clinic, home, and ambulatory blood pressure with increasing age
George S Stergiou1, Angeliki Ntineri1, Anastasios Kollias1
1Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
Insights
Blood pressure measurement differences between clinic (CBP), home (HBP), and daytime ambulatory (dABP) readings vary with age. In children, dABP is higher, while in adults over 30, HBP and dABP are similar and lower than CBP.
Area of Science:
- Cardiology
- Pediatric Hypertension
- Clinical Measurement Science
Background:
- Adult studies show home blood pressure (HBP) and daytime ambulatory blood pressure (dABP) are similar and lower than clinic blood pressure (CBP).
- The influence of age on these blood pressure measurement discrepancies is not well-established.
Purpose of the Study:
- To investigate the impact of age on the differences between CBP, HBP, and dABP measurements.
- To understand how age affects blood pressure monitoring in children, adolescents, and adults.
Main Methods:
- Evaluated 642 untreated individuals (ages 5-78) with CBP, HBP, and dABP within 4 weeks.
- Analyzed data to identify age-related patterns in blood pressure measurement discrepancies.
Main Results:
- In children, dABP exceeded both CBP and HBP.
- Blood pressure differences diminished with age; after 30 years, dABP and HBP became similar and lower than CBP.
- In individuals aged 60 and above, dABP appeared lower than HBP.
Conclusions:
- The relationship between clinic and out-of-office blood pressure measurements is age-dependent.
- Age and hypertension are key predictors of discrepancies among CBP, HBP, and dABP.
- Clinical practice should consider age-specific differences in blood pressure monitoring for accurate hypertension evaluation.
Abstract:
Studies in adults have shown similar levels of home (HBP) and daytime ambulatory blood pressure (dABP), which are lower than clinic blood pressure (CBP) measurements. This study investigated the impact of age on these differences. A total of 642 untreated children, adolescents, and adults referred to a hypertension clinic were evaluated with CBP, HBP, and dABP measurements within 4 weeks (mean age 38.6 ± 19.4 years; range 5-78 years; 61.1% males). In children, dABP was higher than both CBP and HBP. These differences were progressively eliminated with increasing age, and after the age of 30 years, dABP was similar to HBP, and both were lower than CBP. In subjects aged ≥60 years, dABP appeared to be lower than HBP. Age and hypertension appeared to be the main independent predictors of the differences among the three methods.These data suggest that the relationship between office and out-of-office blood pressure measurements is not the same across all age groups and should be taken into account in the evaluation of subjects with elevated blood pressure in clinical practice.
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