[Experimental study of submucous vesical injections in rats. Teflon versus silicone]

Correction of vesicoureteric reflux by endoscopic subureteric injection of polytef paste is an expending procedure. But polytef past is thick, hard to inject and can migrate at distant sites of injection. We have tried a silicone paste on experimental studie observes tissue reaction at the site of injection (bladder) and in pelvic nodes, kidneys, liver, lungs, brain. 22 rats were injected: 8 with polytef paste, 14 with silicone paste. The study demonstrated that polytef paste sub mucosal injection is followed by migration nodes and local granulomatous reaction. The silicone paste is easier to inject; none particules of silicone were found in nodes nor in others visceria; granulomatous reaction and fibrous capsule around foreign body were smaller.