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Thymic B cells promote thymus-derived regulatory T cell development and proliferation

Fang-Ting Lu1, Wei Yang1, Yin-Hu Wang1

  • 1Liver Immunology Laboratory, Institute of Immunology and The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, Anhui 230027, China.

Journal of Autoimmunity
|June 15, 2015
PubMed
Summary

Thymic B cells are crucial for maintaining regulatory T (Treg) cells in the thymus. They promote Treg cell generation and proliferation through cell-cell contact and co-stimulatory molecules, supporting immune homeostasis.

Keywords:
Cell–cell contactDevelopmentProliferationThymic B cellsThymic Treg cells

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