Isolation and characterization of an antimalarial agent of the neem tree Azadirachta indica
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S A Khalid1, H Duddeck, M Gonzalez-Sierra
1Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan.
Journal of Natural Products
|September 1, 1989
Abstract:
The isolation and structure elucidation of gedunin [1], the antimalarial agent of Azadirachta indica, are reported. Its 1H- and 13C-nmr spectra were assigned by using one- and two-dimensional nmr spectroscopy, especially homonuclear and heteronuclear COSY, nOe difference, and COLOC experiments.