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Targeting TNF-Alpha in HIV-1 Infection

Amit Kumar, Laurie Coquard, Georges Herbein1

  • 1Department of Virology, University of Franche-Comte and COMUE Bourgogne Franche-Comte University, CHRU Besancon, Hopital Saint-Jacques, 2 place Saint-Jacques, F-25030 Besancon cedex, France. georges.herbein@univ-fcomte.fr.

Current Drug Targets
|June 16, 2015
PubMed
Summary

Highly active antiretroviral therapy (HAART) combats HIV-1 but drives drug resistance. Tumor necrosis factor alpha (TNF-alpha) inhibition is explored as a novel strategy against HIV-1 pathogenesis and viral reservoirs.

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