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Long-term outcomes following functional endoscopic sinus surgery in Samter's triad
F Olivier1, M George1, D Leuba2
1Otorhinolaryngology Service,Department of ENT,Head and Neck Surgery,Lausanne University Medical Centre (CHUV),Switzerland.
The Journal of Laryngology and Otology
|June 16, 2015
Summary
Functional endoscopic sinus surgery can stabilize Samter's triad progression. However, advanced nasal polyposis (Stage III-IV) negatively impacts long-term outcomes for these patients.
Area of Science:
- Otolaryngology
- Rhinology
- Surgical Outcomes
Background:
- Samter's triad, characterized by asthma, aspirin sensitivity, and nasal polyposis, presents chronic management challenges.
- Functional endoscopic sinus surgery (FESS) is a common treatment, but long-term outcomes require further objective assessment.
Purpose of the Study:
- To evaluate the long-term efficacy of FESS in patients with Samter's triad.
- To correlate objective measures like visual analogue scale (VAS) and nasal endoscopy findings with surgical outcomes.
Main Methods:
- Retrospective analysis of 33 Samter's triad patients undergoing FESS (1987-2007).
- Pre- and post-operative assessment using VAS and nasal endoscopy.
- Patients categorized into two groups based on end-of-follow-up VAS scores.
Main Results:
- Mean follow-up was 11.6 years.
- Group 2 (VAS > 6) showed significantly higher rates of Stage III-IV nasal polyposis (56%) compared to Group 1 (VAS ≤ 6) (4%).
- Advanced polyposis was associated with poorer long-term outcomes.
Conclusions:
- FESS demonstrates a disease-stabilizing effect in Samter's triad patients.
- The presence of Stage III-IV nasal polyposis is a significant negative prognostic factor for long-term outcomes after FESS.
