Related Experiment Video
Updated: Apr 10, 2026
04:04
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
667
Ossifying Parotid Carcinoma ex Pleomorphic Adenoma
Suresh Mohan1, Sidharth V Puram2, Bharat Yarlagadda2
1The Warren Alpert Medical School of Brown University, Providence, RI 02912, USA.
Case Reports in Otolaryngology
|June 16, 2015
Summary
Extensive ossification in parotid masses can mask carcinoma ex pleomorphic adenoma (CXPA). Rigorous pathological analysis is crucial for accurate diagnosis and timely treatment of this rare salivary gland cancer.
Area of Science:
- Otolaryngology
- Surgical Pathology
- Oncology
Background:
- Pleomorphic adenoma is the most common salivary gland neoplasm.
- Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignant transformation of pleomorphic adenoma.
- Extensive ossification within a parotid mass can complicate diagnosis.
Purpose of the Study:
- To report a unique case of extensively ossified CXPA.
- To highlight the diagnostic challenges posed by ossification in parotid masses.
- To emphasize the importance of thorough pathological examination.
Main Methods:
- Case presentation of a 76-year-old male with a slowly growing parotid mass.
- Review of fine-needle aspiration (FNA) cytology and computed tomography (CT) findings.
- Detailed histopathological analysis including decalcification of the ossified mass.
Main Results:
- Initial FNA was nondiagnostic; CT showed a calcified mass.
- Initial pathology suggested a benign lesion, but decalcification revealed noninvasive CXPA.
- Complete surgical resection was performed, with no evidence of disease at nine months follow-up.
Conclusions:
- Extensive ossification can obscure malignant components in parotid tumors.
- Thorough decalcification and pathological examination are essential for diagnosing CXPA.
- Early detection and complete resection are critical for favorable outcomes in CXPA.
