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Published on: February 23, 2014
Morbidity and mortality of bacterial meningitis in Arab children
A A Shaltout1, L T Auger, N B Awadallah
1Department of Pediatrics, Faculty of Medicine, University of Kuwait.
Abstract:
Between September 1981 and March 1987, 92 episodes of bacterial meningitis in 90 children were treated in three major hospitals in Kuwait. The diagnosis was bacteriologically confirmed in 80 (87%). Haemophilus influenzae was the most common aetiological organism and accounted for 42 episodes (45.6%) followed by Streptococcus pneumoniae in 21 (22.8%) and Neisseria meningitidis in only three (3.3%). Bacterial meningitis occurred in 53 children (57.6%) below the age of 1 year and in 81 (88%) below 5 years. The overall case fatality rate was 5.4% and ten children (9%) had severe neurological sequelae of their disease. Sequelae were more common following pneumococcal meningitis (28%) than after Haemophilus (7%). All 12 children with unknown pathogen recovered completely.
Insights
Bacterial meningitis in Kuwaiti children was primarily caused by Haemophilus influenzae. While overall fatality was low, Streptococcus pneumoniae infections led to more severe neurological complications.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Bacterial meningitis remains a significant cause of childhood morbidity and mortality globally.
- Understanding the etiological agents and outcomes of bacterial meningitis is crucial for public health interventions.
Purpose of the Study:
- To investigate the epidemiological characteristics, causative agents, and clinical outcomes of bacterial meningitis in children treated in Kuwait.
Main Methods:
- Retrospective analysis of 92 episodes of bacterial meningitis in 90 children treated between September 1981 and March 1987.
- Bacteriological confirmation of diagnosis and identification of causative organisms.
- Assessment of case fatality rates and neurological sequelae.
Main Results:
- Haemophilus influenzae was the most frequent pathogen (45.6%), followed by Streptococcus pneumoniae (22.8%).
- The majority of cases (88%) occurred in children under 5 years of age.
- The overall case fatality rate was 5.4%, with 9% experiencing severe neurological sequelae, which were more common after pneumococcal meningitis.
Conclusions:
- Haemophilus influenzae is the leading cause of bacterial meningitis in Kuwaiti children.
- Prompt diagnosis and treatment are essential to reduce mortality and long-term neurological deficits.
- Further research into prevention strategies, such as vaccination, is warranted.
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