Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

1.0K
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
1.0K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

680
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
680
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

905
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
905
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

5.8K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
5.8K
Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

1.2K
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1.2K
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

2.1K
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Triggering of viral and bacterial respiratory infection hospitalizations by traffic pollution exposure in a cohort of hospitalized adults.

PloS one·2026
Same author

Change in rate of healthcare encounters for respiratory infection from air pollution exposure after improved vehicle emissions standards in New York State.

Air quality, atmosphere, & health·2026
Same author

Source specific fine particles and rates of asthma and COPD healthcare encounters pre- and post-implementation of the Tier 3 vehicle emissions control regulations.

Journal of hazardous materials·2024
Same author

A case-crossover study of ST-elevation myocardial infarction and organic carbon and source-specific PM<sub>2.5</sub> concentrations in Monroe County, New York.

Frontiers in public health·2024
Same author

Comparison of the rate of healthcare encounters for influenza from source-specific PM<sub>2.5</sub> before and after tier 3 vehicle standards in New York state.

Journal of exposure science & environmental epidemiology·2024
Same author

PM<sub>2.5</sub> and its components and respiratory disease healthcare encounters - Unanticipated increased exposure-response relationships in recent years after environmental policies.

Environmental pollution (Barking, Essex : 1987)·2024

Related Experiment Video

Updated: Apr 10, 2026

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
07:56

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

4.9K

Are pleural plaques an appropriate endpoint for risk analyses?

L Daniel Maxim1, Ronald Niebo, Mark J Utell

  • 1Everest Consulting Associates, Princeton Junction , NJ , USA and.

Inhalation Toxicology
|June 16, 2015
PubMed
Summary

Pleural plaques, often linked to asbestos exposure, do not cause respiratory issues on their own. They may indicate past exposure rather than being an independent risk factor for asbestos-related diseases.

Keywords:
Asbestoslung cancerlung functionmesotheliomanon-malignant respiratory diseaseother natural and synthetic fiberspleural plaquesrespiratory symptomsrisk analysis

More Related Videos

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.8K
A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
05:51

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

13.9K

Related Experiment Videos

Last Updated: Apr 10, 2026

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
07:56

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

4.9K
Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
10:02

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT

Published on: May 2, 2012

18.8K
A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
05:51

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

13.9K

Area of Science:

  • Occupational Health
  • Pulmonology
  • Toxicology

Background:

  • Pleural plaques are a common finding in individuals with occupational or environmental exposure to asbestos and other fibers.
  • The clinical significance and prognostic value of pleural plaques, particularly in relation to asbestos-related diseases, remain subjects of ongoing research and debate.

Purpose of the Study:

  • To review and synthesize the existing literature on the association between pleural plaque development and both non-malignant and malignant diseases in fiber-exposed cohorts.
  • To clarify whether pleural plaques are an independent risk factor or merely a marker of exposure to hazardous fibers.

Main Methods:

  • Systematic literature review of epidemiological studies and cohort analyses.
  • Examination of data correlating pleural plaque presence with respiratory symptoms, lung function, and the incidence of asbestos-related cancers.
  • Analysis of evidence from cohorts exposed to various types of fibers, including those with and without proven carcinogenicity.

Main Results:

  • The presence of pleural plaques, in the absence of other pleural diseases, does not appear to cause respiratory symptoms or significantly impair lung function.
  • A statistical correlation exists between pleural plaque development and malignant diseases for specific types of asbestos.
  • Evidence suggests pleural plaques function as a marker of fiber exposure rather than an independent risk factor for malignant disease.
  • Pleural plaques have also been observed in cohorts exposed to non-carcinogenic fibers.

Conclusions:

  • Pleural plaques alone are not indicative of adverse health outcomes or significant lung function impairment.
  • Pleural plaques serve as a reliable indicator of past exposure to asbestos and other fibers.
  • Future risk assessments for asbestos-related diseases should focus on identifying and mitigating exposure to known hazardous conditions, rather than solely on the presence of pleural plaques.