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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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[A case of so-called carcinosarcoma of the lung]

A Ishikuro1, Y Minami, R Satoh

  • 1Dept. of Int. Med., National Nishi Sapporo Hospital for Chest Diseases.

Gan No Rinsho. Japan Journal of Cancer Clinics
|December 1, 1989
PubMed

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...