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Updated: Apr 10, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
Vulvar yolk sac tumor diagnosed during pregnancy, with recurrence during subsequent second pregnancy
Wen Xu1, Ashley Moon2, Naven Chetty3
1Department of Medical Oncology, Mater Hospital, South Brisbane, QLD, Australia ; University of Queensland, Australia.
Abstract:
•Vulvar yolk sac tumor (YST) is an exceptionally rare and aggressive extra-gonadal germ cell tumor, previously only described in 15 cases in the literature.•We present a unique case of vulvar YST diagnosed during pregnancy, treated with systemic chemotherapy, who subsequently recurred during a second pregnancy.•Despite salvage chemotherapy and autologous stem cell transplantation at recurrence, our patient succumbed to her disease, 31 months post diagnosis.
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