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Acne vulgaris.
1Department of Dermatology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Turk Pediatri Arsivi
|June 17, 2015
Summary
Acne vulgaris is a common inflammatory skin condition affecting the pilosebaceous unit. Effective treatment involves patient-physician communication and can include topical or systemic therapies, with results typically seen in about six months.
Area of Science:
- Dermatology
- Pathology
Background:
- Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, affecting all sexes and races, typically starting at puberty.
- While genetic predisposition is a key factor, the roles of androgens, cosmetics, and diet are limited.
- The pathogenesis involves increased sebum excretion, follicular keratinization, bacterial colonization, and inflammation.
Purpose of the Study:
- To provide a comprehensive overview of acne vulgaris, including its pathogenesis, clinical presentation, and treatment modalities.
Main Methods:
- Review of existing literature on acne vulgaris.
- Discussion of the multifactorial pathogenesis of acne.
- Overview of current topical and systemic treatment options.
Main Results:
- Acne lesions, starting as comedones, can progress to papules, pustules, and cysts.
- Treatment efficacy depends on acne severity and may involve topical agents (benzoyl peroxide, azelaic acid, retinoids, antibiotics) or systemic medications.
- Isotretinoin offers a potential for permanent healing in severe cases.
Conclusions:
- Patient-physician communication is crucial for successful acne management.
- Comprehensive treatment plans, tailored to individual needs, are essential for managing acne vulgaris.
- Achieving significant results from acne treatments typically requires approximately six months of consistent therapy.
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