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Chewing Maintains Hippocampus-Dependent Cognitive Function.

Huayue Chen1, Mitsuo Iinuma2, Minoru Onozuka3

  • 11. Department of Anatomy Gifu University Graduate School of Medicine, Gifu, 501-1194, Gifu, Japan.

International Journal of Medical Sciences
|June 17, 2015
PubMed
Summary
This summary is machine-generated.

Chewing (mastication) supports brain health, particularly the hippocampus, which is vital for memory. Regular chewing may help preserve cognitive function and spatial memory, especially in older adults.

Keywords:
CognitionHippocampusMastication

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Area of Science:

  • Neuroscience
  • Gerontology
  • Physiology

Background:

  • Mastication (chewing) is crucial for food intake and overall health.
  • Emerging research links mastication to cognitive functions, specifically within the hippocampus.
  • The hippocampus is a key brain region for spatial memory and learning.

Purpose of the Study:

  • To review current research on the connection between mastication and hippocampus-dependent cognitive function.
  • To explore the neural pathways linking masticatory organs and the hippocampus.
  • To discuss the implications for cognitive health, particularly in aging populations.

Main Methods:

  • Review of recent animal and human studies.
  • Analysis of neural circuits involved in mastication and hippocampal function.
  • Examination of mechanisms underlying mastication's impact on neurogenesis.

Main Results:

  • Mastication influences cognitive functioning.
  • Masticatory dysfunction correlates with hippocampal impairments and spatial memory deficits, especially in the elderly.
  • Chewing is an effective behavior for maintaining hippocampus-dependent cognitive performance.

Conclusions:

  • Mastication plays a significant role in preserving hippocampus-dependent cognitive function.
  • Chewing may be a valuable strategy for mitigating age-related cognitive decline.
  • Further research into the mechanisms of mastication and hippocampal neurogenesis is warranted.