Related Experiment Video
Updated: Apr 10, 2026

12:44
The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
26.5K
Chondrosarcoma of the Heart
Do Jung Kim1, Jin Hong Wi2, Yonhee Kim3
1Department of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine.
Summary
Chondrosarcoma, a rare cardiac tumor, can cause mitral stenosis. Surgical intervention offers a successful treatment outcome for this challenging condition.
Area of Science:
- Cardiology
- Oncology
- Cardiac Surgery
Background:
- Chondrosarcoma is a rare malignant tumor originating from cartilaginous tissue.
- Cardiac chondrosarcomas are exceptionally rare, with limited literature available.
- The primary treatment for cardiac chondrosarcoma is surgical excision.
Observation:
- A case of chondrosarcoma in the left atrium presented with functional mitral stenosis.
- The tumor's location led to significant hemodynamic compromise, necessitating urgent intervention.
- Despite the rarity and poor prognosis associated with chondrosarcomas, this case required immediate surgical management.
Findings:
- Complete surgical excision of the left atrial chondrosarcoma was successfully performed.
- The patient experienced a successful treatment outcome following the urgent surgical intervention.
- This case highlights the feasibility of surgical management even in complex cardiac tumor presentations.
Implications:
- Successful surgical management of cardiac chondrosarcoma is achievable, even with obstructive symptoms like mitral stenosis.
- Early diagnosis and prompt surgical intervention are crucial for improving outcomes in cardiac chondrosarcoma.
- This case contributes valuable insights into the surgical treatment of rare cardiac tumors, potentially guiding future therapeutic strategies.
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
6.6K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
6.6K
Rous Sarcoma Virus (RSV) and Cancer
6.0K
6.0K
Rheumatic Heart Disease I: Introduction
938
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
938
Cardiomyopathy III: Hypertrophic Cardiomyopathy
754
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
754
Anatomy of the Heart
124.5K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
124.5K
Anatomy of the Heart
5.3K
The heart is a hollow, muscular organ approximately the size of a fist, consisting of four chambers. It is enclosed in the pericardium, a fibrous sac with two layers: the visceral and parietal pericardium, separated by a fluid-filled space containing serous fluid to reduce friction.
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
5.3K

