Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

3.3K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
3.3K
Reticular Dermis01:15

Reticular Dermis

5.5K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
5.5K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

2.3K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
2.3K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Topical Platelet Extract Daily Serum as a Cosmetic Product to Reduce Facial Redness.

The Journal of clinical and aesthetic dermatology·2023
Same author

A Pilot Study of the Safety and Effectiveness of a Novel Device in Subjects With Axillary Hyperhidrosis.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2022
Same author

Self-reported Patient Motivations for Seeking Cosmetic Procedures.

JAMA dermatology·2018
Same author

Anthropometric study of the caucasian nose in the city of Curitiba: relevance of population evaluation.

Brazilian journal of otorhinolaryngology·2017
Same author

Effectiveness of a Nutraceutical During Non-Ablative 1927 nm Fractional Laser on Patients With Facial Hyperpigmentation and Photoaging.

Journal of drugs in dermatology : JDD·2017
Same author

Treatment of retroauricular keloids: Revision of cases treated at the ENT service of HC/UFPR.

International archives of otorhinolaryngology·2015
Same journal

Circulating Tumor DNA as a Biomarker for Melanoma Prognosis and Therapy.

American journal of clinical dermatology·2026
Same journal

Defining the Potential for Disease Modification in Atopic Dermatitis.

American journal of clinical dermatology·2026
Same journal

Atopic Dermatitis: New Targets and Emerging Systemic Therapies.

American journal of clinical dermatology·2026
Same journal

Rethinking Head and Neck Atopic Dermatitis: Pathogenic Axes and Emerging Therapeutic Directions.

American journal of clinical dermatology·2026
Same journal

Correction: Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program.

American journal of clinical dermatology·2026
Same journal

A Systematic Review of the Clinical Impact of GLP-1 Receptor Agonists in Hidradenitis Suppurativa.

American journal of clinical dermatology·2026
See all related articles

Related Experiment Video

Updated: Apr 10, 2026

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
04:36

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components

Published on: July 11, 2025

1.3K

Dermal fillers: an update.

Annelyse Cristine Ballin1, Fredric S Brandt2,3,4, Alex Cazzaniga2

  • 1Facial Plastic Surgery, Department of Otolaryngology, Federal University of Parana, Rua General Carneiro, 181, Curitiba, PR, 80060-900, Brazil. annelysecb@gmail.com.

American Journal of Clinical Dermatology
|June 18, 2015
PubMed
Summary
This summary is machine-generated.

Dermal fillers are widely used for cosmetic procedures like wrinkle reduction and facial contouring. This review examines filler properties, safety, and trends to guide healthcare providers in selecting optimal treatment options for patients.

More Related Videos

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

1.7K
Mechanical Micronization of Lipoaspirates for Regenerative Therapy
05:02

Mechanical Micronization of Lipoaspirates for Regenerative Therapy

Published on: March 15, 2019

8.3K

Related Experiment Videos

Last Updated: Apr 10, 2026

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
04:36

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components

Published on: July 11, 2025

1.3K
Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
03:47

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application

Published on: September 27, 2024

1.7K
Mechanical Micronization of Lipoaspirates for Regenerative Therapy
05:02

Mechanical Micronization of Lipoaspirates for Regenerative Therapy

Published on: March 15, 2019

8.3K

Area of Science:

  • Dermatology
  • Cosmetic Surgery
  • Aesthetic Medicine

Background:

  • Dermal filler injections are the second most common nonsurgical cosmetic procedure in the USA.
  • Fillers address volume loss, scars, wrinkles, and are used for facial sculpting and lip augmentation.
  • The variety of available injectable dermal fillers is continuously expanding.

Purpose of the Study:

  • To provide a comprehensive review of currently available dermal filler properties.
  • To analyze how filler characteristics influence selection for specific patient needs and anatomical sites.
  • To discuss current trends in dermal filler injections.

Main Methods:

  • Extensive literature review of dermal filler properties.
  • Analysis of rheology, longevity, and adverse effect profiles of various filler agents.
  • Discussion of clinical application trends and considerations.

Main Results:

  • Dermal filler properties vary significantly, impacting their suitability for different cosmetic applications.
  • Understanding rheology, longevity, and potential adverse effects is crucial for safe and effective use.
  • Current trends indicate a growing market and evolving patient demands for aesthetic treatments.

Conclusions:

  • Dermatologists and cosmetic surgeons must stay informed about filler advancements to ensure patient safety and optimal outcomes.
  • Selection of dermal fillers should be based on a thorough assessment of filler characteristics and patient-specific factors.
  • This review aims to support clinicians in making informed decisions regarding dermal filler treatments.