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Published on: May 28, 2019
Clinical Outcomes of Early Repatriation for Patients With ST-Segment Elevation Myocardial Infarction: A
Wael Abuzeid1, Maria Bennell2, Feng Qiu3
1Schulich Heart Center, Sunnybrook Health Sciences Center, Division of Cardiology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Insights
Early transfer of ST-elevation myocardial infarction (STEMI) patients after PCI to non-PCI centers increases readmission for myocardial infarction (MI). Further research is needed to assess the safety of this early repatriation strategy.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Services Research
Background:
- Hospital resource limitations often necessitate early repatriation of ST-elevation myocardial infarction (STEMI) patients post-primary percutaneous coronary intervention (PCI) to non-PCI centers.
- The safety and implications of this early transfer strategy remain incompletely understood.
- This study addresses the clinical safety of repatriating STEMI patients to non-PCI facilities after successful PCI.
Purpose of the Study:
- To evaluate the safety of early patient repatriation from PCI centers to non-PCI centers for STEMI patients.
- To compare the outcomes of STEMI patients repatriated early versus those remaining at the PCI center.
Main Methods:
- A cohort of STEMI patients undergoing primary PCI between 2010-2012 was identified.
- Patients with shock or early mortality were excluded; propensity score matching was used to compare repatriated and non-repatriated groups.
- One-year all-cause mortality and readmission for recurrent myocardial infarction (MI) were the primary outcomes assessed.
Main Results:
- 430 well-matched pairs of STEMI patients were analyzed.
- No significant difference in 1-year all-cause mortality was observed between repatriated and non-repatriated groups (6.7% vs. 5.6%).
- However, the 1-year readmission rate for MI was significantly higher in the repatriated group (12.1%) compared to the non-repatriated group (5.8%).
Conclusions:
- Early repatriation of STEMI patients after primary PCI to non-PCI centers is associated with a significantly increased risk of readmission for myocardial infarction.
- This finding raises concerns about the safety of early repatriation strategies.
- Further investigation is warranted to fully understand the implications and optimize care pathways for STEMI patients transferred from PCI centers.
Background:
Because of limitations on hospital resources, patients with ST-elevation myocardial infarction (STEMI) who undergo successful primary percutaneous coronary intervention (PCI) are often repatriated to non-PCI centres. However, the safety of this practice is not clear. Our objective was to evaluate the safety of early repatriation of STEMI patients after PCI to a non-PCI centre, compared with ongoing treatment at the PCI centre.
Methods:
Consecutive STEMI patients, who received primary PCI at 1 of 4 PCI hospitals in Toronto, Canada between 2010 and 2012 were identified. Patients with shock or who died within 24 hours of presentation were excluded. Outcomes of interest were all-cause mortality and readmission for recurrent myocardial infarction (MI) at 1 year. To account for confounding because of the observational nature of our data, propensity score-matched pairs of patients who were repatriated vs nonrepatriated were identified.
Results:
Using the propensity score, 430 well matched pairs were identified, representing our cohort. There was no significant difference between repatriated and nonrepatriated groups in 1-year mortality (repatriated: 6.7%, nonrepatriated: 5.6%, hazard ratio, 1.18; 95% confidence interval, 0.69-2.03; P = 0.545). The 1-year readmission rates for MI were significantly greater for the repatriated group compared with the nonrepatriated group (repatriated: 12.1%; nonrepatriated: 5.8%; hazard ratio, 2.09; 95% confidence interval, 1.30-3.36; P = 0.002).
Conclusions:
A strategy of early repatriation of STEMI patients was associated with a greater rate of readmission for MI. Our study raises questions regarding the safety of an early repatriation strategy that merit further research.
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