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Image-guided drug delivery: preclinical applications and clinical translation
Tarun Ojha1, Larissa Rizzo, Gert Storm
1RWTH Aachen University, University Clinic and Helmholtz Institute for Biomedical Engineering, Institute for Experimental Molecular Imaging (ExMI), Department of Nanomedicines and Theranostics , Pauwelsstrasse 30, 52074 Aachen , Germany.
Abstract:
Image-guided drug delivery refers to the combination of drug targeting and imaging. Preclinically, image-guided drug delivery can be used for several different purposes, including for monitoring biodistribution, target site accumulation, off-target localization, drug release and drug efficacy. Clinically, it holds significant potential for preselecting patients. In this editorial, we briefly summarize the main principles of image-guided drug delivery, and we describe its potential for facilitating, furthering and personalizing nanomedicine treatments.
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