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Related Concept Videos

Global Regulatory Systems01:28

Global Regulatory Systems

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Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
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Drug Control Governance: Regulatory Bodies and Their Impact01:03

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Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Cis-regulatory Sequences02:02

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Cis-regulatory Sequences02:02

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Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
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Master Transcription Regulators02:23

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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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Neural Regulation01:37

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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Related Experiment Video

Updated: Apr 9, 2026

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
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Advancing a Vision for Regulatory Science Training.

Joan E Adamo1, Erin E Wilhelm2, Scott J Steele3

  • 1Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, New York, USA.

Clinical and Translational Science
|June 18, 2015
PubMed
Summary

This study identifies essential competencies for regulatory science, a growing field integrating science, law, and policy in medical applications. It offers recommendations to improve education and training through a multifaceted approach.

Keywords:
competenciesregulatory sciencetrainingtranslational science

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Area of Science:

  • Regulatory science is an interdisciplinary field combining science, law, and policy, crucial for medical product development and oversight.

Background:

  • The discipline of regulatory science is expanding, necessitating clear definitions and quality assessment criteria.
  • Competencies are vital for defining the scope of regulatory science and evaluating educational programs.

Framework:

  • This paper outlines key competencies identified for the field of regulatory science.
  • The development process for these regulatory science competencies is detailed.

Implementation:

  • Recommendations are provided to enhance educational and training initiatives within regulatory science.
  • A multifaceted training strategy is proposed to build expertise in this domain.

Implications:

  • Establishing defined competencies will standardize regulatory science education.
  • Improved training will foster a more skilled workforce, advancing medical innovation and public health protection.