NDM-1- or OXA-48-producing Enterobacteriaceae colonising Polish tourists following a terrorist attack in Tunis, March

R Izdebski1, K Bojarska, A Baraniak

  • 1National Reference Centre for Susceptibility Testing & Department of Molecular Microbiology, National Medicines Institute, Warsaw, Poland.

Insights

Two patients imported carbapenemase-producing Enterobacteriaceae (CPE) strains, including NDM-1 and OXA-48, to Poland from Tunisia. This highlights the need for screening travelers from endemic regions to prevent CPE spread.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Carbapenemase-producing Enterobacteriaceae (CPE) are a growing global health threat.
  • Tunisia is an area where CPE are endemic.
  • Travel can facilitate the international spread of antibiotic-resistant bacteria.

Purpose of the Study:

  • To report the introduction of NDM-1 and OXA-48 producing Enterobacteriaceae strains into Poland.
  • To emphasize the importance of microbiological screening for travelers returning from high-risk areas.

Main Methods:

  • Case report describing two patients with travel history to Tunisia.
  • Identification of bacterial isolates and their antibiotic resistance genes.

Main Results:

  • Introduction of Klebsiella pneumoniae ST147 and Escherichia coli ST410 strains producing New Delhi metallo-beta-lactamase 1 (NDM-1).
  • Introduction of OXA-48-producing K. pneumoniae ST101 strain.
  • Both strains were identified in patients returning from Tunisia after hospitalization.

Conclusions:

  • Patients returning from countries with endemic carbapenemase-producing Enterobacteriaceae pose a risk of introducing these resistant strains.
  • Microbiological screening of patients upon admission to healthcare facilities is crucial, especially after travel to endemic regions.
  • This case underscores the importance of global surveillance and infection control measures to combat the spread of antibiotic resistance.

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