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NDM-1- or OXA-48-producing Enterobacteriaceae colonising Polish tourists following a terrorist attack in Tunis, March
R Izdebski1, K Bojarska, A Baraniak
1National Reference Centre for Susceptibility Testing & Department of Molecular Microbiology, National Medicines Institute, Warsaw, Poland.
Abstract:
We describe the introduction of NDM-1-producing Klebsiella pneumoniae ST147 and Escherichia coli ST410, and OXA-48-producing K. pneumoniae ST101 strains to Poland by two patients transported to the country after hospitalisation in Tunisia. The patients had gunshot wounds following the terrorist attack in the Bardo National Museum in Tunis in March 2015. Our report reinforces the need for microbiological screening of patients returning from travel on admission to healthcare institutions, especially following hospitalisation in countries where carbapenemase-producing Enterobacteriaceae are endemic.
Insights
Two patients imported carbapenemase-producing Enterobacteriaceae (CPE) strains, including NDM-1 and OXA-48, to Poland from Tunisia. This highlights the need for screening travelers from endemic regions to prevent CPE spread.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Carbapenemase-producing Enterobacteriaceae (CPE) are a growing global health threat.
- Tunisia is an area where CPE are endemic.
- Travel can facilitate the international spread of antibiotic-resistant bacteria.
Purpose of the Study:
- To report the introduction of NDM-1 and OXA-48 producing Enterobacteriaceae strains into Poland.
- To emphasize the importance of microbiological screening for travelers returning from high-risk areas.
Main Methods:
- Case report describing two patients with travel history to Tunisia.
- Identification of bacterial isolates and their antibiotic resistance genes.
Main Results:
- Introduction of Klebsiella pneumoniae ST147 and Escherichia coli ST410 strains producing New Delhi metallo-beta-lactamase 1 (NDM-1).
- Introduction of OXA-48-producing K. pneumoniae ST101 strain.
- Both strains were identified in patients returning from Tunisia after hospitalization.
Conclusions:
- Patients returning from countries with endemic carbapenemase-producing Enterobacteriaceae pose a risk of introducing these resistant strains.
- Microbiological screening of patients upon admission to healthcare facilities is crucial, especially after travel to endemic regions.
- This case underscores the importance of global surveillance and infection control measures to combat the spread of antibiotic resistance.
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