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Protein kinase C deficiency in juvenile chronic myeloid leukemia: a case report
P Courtois1, A Ferster, P Fondu
1Faculty of Medicine, Department of Pediatrics, Free University of Brussels, Belgium.
Nouvelle Revue Francaise D'Hematologie
|January 1, 1989
Abstract:
Protein kinase C activity was assayed in morphologically differentiated and undifferentiated myeloid cells of a 13-month-old girl with chronic myeloid leukemia. A reduced protein kinase C activity was seen in the morphologically differentiated neutrophils, while the activity in the leukemic cells was higher to that of normal neutrophils from control subjects.