Related Experiment Video
Updated: Apr 9, 2026

Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
Morphometric facial analysis: a methodology to create lateral facial images
Koohyar Karimi1, Zlatko Devcic2, Natalie Popenko3
1UC Irvine Otolaryngology-Head and Neck Surgery, Loma Linda University School of Dentistry, 24942 Silverleaf Ln., Laguna Hills, CA, 92653, USA. kkarimi@llu.edu.
Introduction:
Currently, the majority of research in facial analysis using computational morphing methods focuses exclusively on analysis of frontal facial projections. Lateral facial morphing analysis has not been extensively investigated, and landmark features critical to specify registry points are unknown. This study aims to (1) determine the quantity of registry points (RP) required to create realistic lateral faces and (2) determine key facial registry point landmarks required to create synthetic lateral faces.
Method:
36 synthetic lateral faces with a 50 to 250 RP were created to determine the ideal quantity of RP to create a realistic lateral image; ear, eyebrow, eye, nose, lips, hairline, facial outline, and overall outline were evaluated by an expert panel of seven evaluators using a 1 to 5 point Lickert scale rating system.
Result:
ANOVA single-variable analyses revealed significant differences when comparing templates of 200 and 250 RP with 50 and 100 RP templates (p < 0.05). Furthermore, analysis of all key landmark areas of the face indicated significant differences between different registry points except for 200 and 250 registry point markers. Kruskal-Wallis statistical analysis revealed the landmarks varied significantly from 50 to 200 RP,but had no significance with 200 and 250 RP.
Conclusion:
The most ideal quantity of RP used for the creation of realistic lateral faces was in the range of 200 RP. Defined lateral facial registry point landmarks generated successful realistic faces.
More Related Videos
08:03Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
06:48Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
Published on: June 7, 2024