Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

16.8K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
16.8K
Genomics02:02

Genomics

41.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.8K
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

54.3K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
54.3K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.3K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

50.8K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
50.8K
Genetic Screens02:46

Genetic Screens

5.9K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vulnerability, protection and fairness: ethical and regulatory limits in small-N gene therapy trials.

Trials·2026
Same author

Moral Attitudes on Somatic Gene Editing for Inherited Cardiomyopathy: A Qualitative Interview Study with Key Stakeholders in the Netherlands.

Journal of bioethical inquiry·2026
Same author

Routes to expanded carrier screening in the UK: The perspectives of professional stakeholders.

Journal of community genetics·2026
Same author

Anonymization, accountability, and access: legal dimensions of health data sharing in federated networks. Perspectives from empirical study.

Frontiers in digital health·2026
Same author

What patients value in data reuse for oncology research: a multi-stakeholder qualitative study to inform the European Health Data Space implementation in Belgium and beyond.

Archives of public health = Archives belges de sante publique·2026
Same author

Harmful anachronism: World Athletics reinstates gene testing to participate in women's competitions.

British journal of sports medicine·2026

Related Experiment Video

Updated: Apr 9, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.6K

Challenges of web-based personal genomic data sharing.

Mahsa Shabani1, Pascal Borry

  • 1Centre for Biomedical Ethics and Law, Department of Public Health and Primary Care, University of Leuven, Kapucijnenvoer 35, Box 7001, 3000, Leuven, Belgium, mahsa.shabani@med.kuleuven.be.

Life Sciences, Society and Policy
|June 19, 2015
PubMed
Summary
This summary is machine-generated.

Individuals are increasingly sharing personal genomic data for research. This trend necessitates awareness of potential privacy risks and the need for informed consent to balance benefits and harms.

More Related Videos

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K

Related Experiment Videos

Last Updated: Apr 9, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.6K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.5K

Area of Science:

  • Genomics
  • Bioinformatics
  • Medical Ethics

Background:

  • Growing availability and sharing of phenotypic and genotypic data are crucial for studying gene-disease relationships.
  • Individuals are increasingly sharing personal genomic data through online platforms and private test providers.
  • Initiatives emphasize individual control over personal genomic data for research benefits.

Purpose of the Study:

  • To explore the challenges associated with individual personal genomic data sharing initiatives.
  • To highlight the necessity of individual awareness regarding the implications of sharing genomic data.
  • To consider privacy risks and potential harms from unintended data uses.

Main Methods:

  • Review of current personal genomic data sharing initiatives and platforms.
  • Analysis of ethical considerations and challenges in data sharing.
  • Examination of privacy risks and de-identification controversies.

Main Results:

  • Personal genomic data sharing is facilitated by accessible technology and online networks.
  • Emphasis is placed on individual control and consent in data sharing.
  • Significant privacy risks and challenges related to data de-identifiability exist.

Conclusions:

  • Individuals must be aware of the risks and benefits when sharing their genomic data.
  • Ensuring awareness of implications for individuals and families is essential.
  • Addressing privacy concerns and potential harms from unintended data use is critical for responsible data sharing.