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Cesarean delivery and metabolic risk factors in young adults: a Brazilian birth cohort study

Juliana Rombaldi Bernardi1, Tanara Vogel Pinheiro2, Noel Theodore Mueller3

  • 1Biological and Health Sciences Center, University of Caxias do Sul, Caxias do Sul, Brazil; Department of Pediatrics, Porto Alegre Clinical Hospital, Faculty of Medicine, University of Rio Grande do Sul, Porto Alegre, Brazil;

The American Journal of Clinical Nutrition
|June 19, 2015
PubMed

Insights

Cesarean delivery is linked to higher body mass index (BMI) in young adults, but not other metabolic risks. This study examined the long-term health impacts of delivery method on metabolic health.

Area of Science:

  • Public Health
  • Epidemiology
  • Metabolic Health

Background:

  • Cesarean delivery (CD) impacts infant gut microbiome and is linked to obesity.
  • The association between CD and metabolic risk factors in young adults remains unclear.

Purpose of the Study:

  • To investigate the association between Cesarean delivery (CD) and metabolic risk factors in young adults.
  • To analyze long-term health outcomes related to delivery method.

Main Methods:

  • A cohort study in Brazil followed 2063 subjects for 23-25 years.
  • Data included delivery type, birth weight, maternal factors, and adult anthropometric and biochemical measurements.
  • Linear regression controlled for confounders to assess CD's association with metabolic factors.

Main Results:

  • Cesarean delivery (32.0%) was associated with higher body mass index (BMI) in young adults (23-25 years).
  • No significant association was found between CD and glucose, insulin resistance, or lipid profiles.
  • CD was more common in older and more educated mothers.

Conclusions:

  • Cesarean delivery is associated with increased BMI in young adulthood.
  • CD does not appear to be linked to other key metabolic risk factors like insulin resistance or dyslipidemia in this population.
Abstract

Keywords:
cesarean deliverycohort studymetabolic diseasesmicrobiomeobesityvaginal delivery

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