Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypercalcaemia associated with chronic viral hepatitis.

J F Cadranel1, J Cadranel, C Buffet

  • 1Service des Maladies du Foie et de l'Appareil Digestif, Hôpital de Bicêtre, France.

Postgraduate Medical Journal
|September 1, 1989
PubMed
Summary

This study reports a rare case of prolonged hypercalcemia in a patient with chronic hepatitis B. The findings suggest hypercalcemia may be a rare feature of advanced liver disease, requiring further investigation into its mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world external control arm for the single-arm LIBRETTO-001 trial of selpercatinib in RET-mutation-positive medullary thyroid cancer: RECALIB-RET.

ESMO open·2026
Same author

Practical implementation of automated insulin delivery systems in 2025: A French position statement update.

Diabetes & metabolism·2025
Same author

Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration.

Journal of endocrinological investigation·2024
Same author

Normal Parathyroid Glands Are Most Often Seen on Neck Ultrasound.

Academic radiology·2024
Same author

Clinico-pathological factors associated with radioiodine refractory differentiated thyroid carcinoma status.

Journal of endocrinological investigation·2024
Same author

SFE-AFCE-SFMN 2022 consensus on the management of thyroid nodules: Synthesis and algorithms.

Annales d'endocrinologie·2022

Area of Science:

  • Endocrinology
  • Hepatology
  • Nephrology

Background:

  • Hypercalcemia is a common metabolic disorder with various underlying causes.
  • Chronic liver disease, particularly hepatitis B virus infection, can present with complex metabolic alterations.

Observation:

  • A patient with chronic hepatitis B infection presented with persistent hypercalcemia.
  • Hepatocellular carcinoma and bone malignancy were excluded as causes.
  • The patient exhibited normal serum phosphate, low nephrogenic cyclic AMP, and increased tubular phosphate reabsorption.

Findings:

  • The observed hypercalcemia was not mediated by parathyroid hormone.
  • The biological profile (normal phosphataemia, low nephrogenic cAMP, high tubular phosphate reabsorption) ruled out common causes of hypercalcemia.

Related Experiment Videos

  • This case highlights a potential, rare association between advanced liver disease and hypercalcemia.

    • Implications:

    • Hypercalcemia could be an unrecognized paraneoplastic or metabolic complication of advanced chronic liver disease.
    • Further research is needed to elucidate the specific mechanisms linking chronic hepatitis B and hypercalcemia.
    • This case underscores the importance of considering liver disease in the differential diagnosis of unexplained hypercalcemia.