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Updated: Apr 9, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Sleep duration, cognitive decline, and dementia risk in older women
Jiu-Chiuan Chen1, Mark A Espeland2, Robert L Brunner3
1Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
Introduction:
Consistent evidence linking habitual sleep duration with risks of mild cognitive impairment (MCI) and dementia is lacking.
Methods:
We conducted a prospective study on 7444 community-dwelling women (aged 65-80 y) with self-reported sleep duration, within the Women's Health Initiative Memory Study in 1995-2008. Incident MCI/dementia cases were ascertained by validated protocols. Cox models were used to adjust for multiple sociodemographic and lifestyle factors, depression, cardiovascular disease (CVD), and other clinical characteristics.
Results:
We found a statistically significant (P = .03) V-shaped association with a higher MCI/dementia risk in women with either short (≤6 hours/night) or long (≥8 hours/night) sleep duration (vs. 7 hours/night). The multicovariate-adjusted hazard for MCI/dementia was increased by 36% in short sleepers irrespective of CVD, and by 35% in long sleepers without CVD. A similar V-shaped association was found with cognitive decline.
Discussion:
In older women, habitual sleep duration predicts the future risk for cognitive impairments including dementia, independent of vascular risk factors.
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