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Updated: Apr 9, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Imaging Evaluation of Mediastinal Masses in Children and Adults: Practical Diagnostic Approach Based on A New
Paul G Thacker1, Maryam G Mahani, Amer Heider
1*Assistant Professor, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC †Assistant Professor, Department of Radiology, Division of Cardiothoracic Radiology and Section of Pediatric Radiology, University of Michigan, C.S. Mott Children's Hospital ‡Assistant Professor of Pathology, Department of Pathology, University of Michigan Health System, Ann Arbor, MI §Chief, Division of Thoracic Imaging, Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA.
Abstract:
A compartmental approach to the diagnosis of the mediastinal masses in children and adults has been widely used to facilitate the diagnosis and planning of diagnostic interventions and surgical treatment for many years. Recently, a new computed tomography-based mediastinal division scheme, approved by the International Thymic Malignancy Interest Group, has received considerable attention as a potential new standard. In this review article, this new computed tomography-based mediastinal division scheme is described and illustrated. In addition, currently used imaging modalities and techniques, practical imaging algorithm of evaluating mediastinal masses, and characteristic imaging findings of various mediastinal masses that occur in children and adults are discussed. Such up-to-date knowledge has the potential to facilitate better understanding of mediastinal masses in both pediatric and adult populations.
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