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Updated: Apr 9, 2026

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
Published on: May 4, 2018
Detection of low concentrations of ampicillin in milk
Chrysafis Andreou1, Rustin Mirsafavi, Martin Moskovits
1Institute of Collaborative Biotechnologies, University of California, Santa Barbara, California 93106, USA. meinhart@engineering.ucsb.edu.
Abstract:
Ampicillin, a common antibiotic, is detected at trace concentrations in milk using surface enhanced Raman spectroscopy in a microfluidic device, using less than 20 μL of sample, in 10 minutes, with minimal off-chip preparation. The device is configured so as to favor the interaction of the analyte with colloidal silver, and the optimization of the aggregation of the silver nanoparticles so as to increase the SERS intensity and the consequential sensitivity of analyte detection.

