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[Chronic heart failure : current guideline recommendations and innovations]

S Ewen1, F Mahfoud, M Böhm

  • 1Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Deutschland, sebastian.ewen@uks.eu.

Der Internist
|June 20, 2015
PubMed

Insights

This review highlights 2014 innovations in chronic heart failure therapy, including updated guidelines and new medications like ARNI (angiotensin receptor-neprilysin inhibitors). It also covers managing comorbidities such as atrial fibrillation and hyperkalemia.

Area of Science:

  • Cardiology
  • Pharmacology
  • Internal Medicine

Context:

  • Chronic heart failure (CHF) is a global health concern with rising prevalence.
  • Standardized, evidence-based treatment is crucial due to high morbidity and mortality.
  • European Society of Cardiology (ESC) guidelines provide a framework for CHF management.

Purpose:

  • To provide an overview of key innovations in chronic heart failure management from 2014.
  • To highlight updates to established therapies and introduce novel pharmacological agents.
  • To discuss new insights into managing common comorbidities in CHF patients.

Summary:

  • Reviews advancements in established CHF medications, including beta-blockers and mineralocorticoid receptor antagonists.
  • Introduces the novel drug class Angiotensin Receptor-Neprilysin Inhibitors (ARNI).
  • Addresses updated management strategies for comorbidities like atrial fibrillation and hyperkalemia.

Impact:

  • Facilitates the adoption of updated, evidence-based treatment protocols for chronic heart failure.
  • Informs clinicians about new therapeutic options, potentially improving patient outcomes.
  • Enhances the comprehensive management of complex CHF patients with multiple comorbidities.

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