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Updated: Apr 9, 2026
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
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[Chronic heart failure : current guideline recommendations and innovations]
1Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Deutschland, sebastian.ewen@uks.eu.
Der Internist
|June 20, 2015
Summary
This review highlights 2014 innovations in chronic heart failure therapy, including updated guidelines and new medications like ARNI (angiotensin receptor-neprilysin inhibitors). It also covers managing comorbidities such as atrial fibrillation and hyperkalemia.
Area of Science:
- Cardiology
- Pharmacology
- Internal Medicine
Context:
- Chronic heart failure (CHF) is a global health concern with rising prevalence.
- Standardized, evidence-based treatment is crucial due to high morbidity and mortality.
- European Society of Cardiology (ESC) guidelines provide a framework for CHF management.
Purpose:
- To provide an overview of key innovations in chronic heart failure management from 2014.
- To highlight updates to established therapies and introduce novel pharmacological agents.
- To discuss new insights into managing common comorbidities in CHF patients.
Summary:
- Reviews advancements in established CHF medications, including beta-blockers and mineralocorticoid receptor antagonists.
- Introduces the novel drug class Angiotensin Receptor-Neprilysin Inhibitors (ARNI).
- Addresses updated management strategies for comorbidities like atrial fibrillation and hyperkalemia.
Impact:
- Facilitates the adoption of updated, evidence-based treatment protocols for chronic heart failure.
- Informs clinicians about new therapeutic options, potentially improving patient outcomes.
- Enhances the comprehensive management of complex CHF patients with multiple comorbidities.
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