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Comprehensive assessment of morphology and severity of atrial septal defects in adults by CT

Kazuhiro Osawa1, Toru Miyoshi1, Yusuke Morimitsu2

  • 1Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558, Japan.

Journal of Cardiovascular Computed Tomography
|June 20, 2015
PubMed

Insights

Cardiac CT effectively assesses secundum atrial septal defects (ASD) in adults. It accurately measures defect size and pulmonary to systemic blood flow ratio, proving its clinical utility.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Diagnostic Tools

Background:

  • Cardiac CT is valuable for visualizing secundum atrial septal defect (ASD) anatomy.
  • Comprehensive assessment of CT's hemodynamic evaluation, including pulmonary to systemic blood flow ratio (Qp/Qs), is lacking.

Purpose of the Study:

  • Evaluate CT's utility in assessing hemodynamics of secundum ASD in adults.
  • Compare CT findings with transesophageal echocardiography (TEE), transthoracic echocardiography, and invasive catheterization.

Main Methods:

  • Fifty adult secundum ASD patients underwent 128-slice multidetector CT.
  • 2D reconstruction determined ASD size, rim length, and Qp/Qs ratio.
  • Comparisons were made with TEE, transthoracic echocardiography, and catheterization data.

Main Results:

  • CT and TEE showed comparable ASD maximum sizes (21.2 ± 8.0 vs. 20.0 ± 7.3 mm).
  • Comparable rim lengths were observed between CT and TEE measurements.
  • CT-derived Qp/Qs ratios closely matched invasive catheterization results (2.3 ± 0.7 vs. 2.3 ± 0.8).

Conclusions:

  • Cardiac CT is feasible for assessing secundum ASD pathology in adults.
  • CT provides reliable measurements for defect size and hemodynamic assessment.
  • CT is a viable tool for evaluating the severity of secundum ASD.
Abstract

Keywords:
Atrial septum defectCardiac computed tomographyCongenital heart diseaseEchocardiographyStructural heart disease

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