Related Experiment Video
Updated: Apr 9, 2026
08:39
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
5.6K
Bladder cancer in the elderly patient: challenges and solutions
Elizabeth A Guancial1, Breton Roussel2, Derek P Bergsma3
1Division of Hematology/Oncology, Department of Medicine, Wilmot Cancer Institute, University of Rochester Medical Center School of Medicine and Dentistry, Rochester, NY, USA.
Clinical Interventions in Aging
|June 20, 2015
Summary
Bladder cancer disproportionately affects the elderly, often leading to undertreatment and poorer outcomes. Individualizing care based on fitness, not just age, improves treatment for older adults.
Area of Science:
- Geriatric Oncology
- Urologic Oncology
Background:
- Bladder cancer (BC) predominantly affects elderly individuals.
- Elderly patients face higher risks of treatment toxicity due to comorbidities.
- This population often receives suboptimal treatment, resulting in worse outcomes.
Purpose of the Study:
- To address the disparity in bladder cancer treatment for elderly patients.
- To promote individualized treatment strategies based on functional status.
- To optimize curative therapy for fit elderly patients and mitigate risks for frail individuals.
Main Methods:
- Utilizing a comprehensive geriatric assessment framework.
- Balancing patient health, treatment risks, and cancer aggressiveness.
- Individualizing treatment decisions based on functional status over chronological age.
Main Results:
- The study highlights the need for tailored approaches in elderly bladder cancer patients.
- Functional status assessment aids in optimizing treatment strategies.
- Individualized care can improve outcomes and reduce toxicity in this vulnerable group.
Conclusions:
- Personalized treatment strategies are crucial for elderly bladder cancer patients.
- Comprehensive geriatric assessment is key to balancing treatment benefits and risks.
- Further research into novel systemic therapies and reduced morbidity interventions is needed.
Related Concept Videos
01:28Urinary Tract Calculi V: Nursing Management
447
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
447
01:17Urinary Tract Infection IV: Nursing Management
604
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
604
01:15Drug Dosing: Geriatric Patients
359
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
359
01:30Urinary Tract Calculi III: Medical Management
349
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
349
01:25Urinary Tract Calculi VI: Surgical Management
881
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
881
01:21Nursing Assessment of the Genitourinary System I: Health History
593
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
593