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Updated: Apr 9, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

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Published on: July 3, 2014

Endobiliary Stent Position Changes during External-beam Radiotherapy.

Kwun-Ye Chu¹, Cynthia L Eccles¹, Thomas B Brunner²

¹CRUK/MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom ; Radiotherapy Department, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

Journal of Medical Imaging and Radiation Sciences

|June 20, 2015

Summary

This summary is machine-generated.

Endobiliary stents show potential for pancreatic localization during radiotherapy. However, some patients experienced significant interfraction stent migration, requiring further investigation for reliable use in image-guided treatment.

Keywords:

Stent cone-beam CT image-guided radiotherapy pancreatic cancer position change

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Area of Science:

Radiation Oncology
Medical Imaging
Gastroenterology

Background:

Endobiliary stents are explored as surrogates for pancreatic localization.
Accurate localization is crucial for effective external-beam radiotherapy (EBRT) in locally advanced pancreatic cancer (LAPC).

Purpose of the Study:

To assess interfraction changes in endobiliary stent position during EBRT for LAPC.
To evaluate the reliability of endobiliary stents as surrogates for pancreatic target localization.

Main Methods:

Six LAPC patients with endobiliary stents undergoing EBRT were analyzed.
Daily cone-beam computed tomography (CBCT) scans were used to measure stent position relative to the L1 vertebra.
Interfraction changes were compared between daily CBCTs and planning CT scans.

Main Results:

Three patients exhibited mean interfraction stent position changes of ≥1 cm.
Significant stent migration (right, inferior, posterior, superior) was observed in specific patients.
Three patients showed minimal interfraction position changes (<1 cm).

Conclusions:

Endobiliary stent migration and deformation occurred in a subset of patients.
Further research is needed to validate endobiliary stents for LAPC target localization in image-guided EBRT.