Related Experiment Video
Updated: Apr 9, 2026

04:38
A Murine Tail Lymphedema Model
Published on: February 10, 2021
6.9K
Lymphatic Interventions for Treatment of Chylothorax
H H Schild1, C P Naehle1, K E Wilhelm1
1Department of Radiology, University Hospital, Bonn, Germany.
Summary
Lymphatic interventional procedures, including thoracic duct embolization, effectively treat chylothorax. These minimally invasive techniques offer a viable alternative when surgery fails and should be considered early in management.
Area of Science:
- Interventional Radiology
- Thoracic Surgery
- Lymphatic System
Background:
- Chylothorax, characterized by lymphatic fluid in the pleural space, presents a significant clinical challenge.
- Therapy-resistant cases often require advanced interventions beyond conservative management.
Purpose of the Study:
- To evaluate the efficacy of lymphatic interventional procedures for treating chylothorax.
- To assess the success rates and potential complications of these minimally invasive techniques.
Main Methods:
- Retrospective analysis of lymphatic interventions performed between 2001 and 2014.
- Detailed review of 21 patients with therapy-resistant chylothorax undergoing procedures like thoracic duct embolization, lymphatic vessel destruction, and ethanol injection.
Main Results:
- Lymphatic radiological interventions were technically successful in 19 out of 21 patients.
- Thoracic duct embolization achieved clinical cure in 82.3% (14/17) of cases, including patients with prior failed surgical ligation.
- Percutaneous lymphatic destruction and ethanol injection also demonstrated clinical effectiveness.
Conclusions:
- Interventional lymphatic procedures are effective treatment options for chylothorax.
- These minimally invasive techniques should be considered early in the treatment algorithm for chylothorax.
- Thoracic duct embolization is a primary interventional choice, with alternative percutaneous methods available if embolization is not feasible.
Related Concept Videos
Lymphatic Vessels and Lymph Transport
24.8K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
24.8K
Endoscopic Studies II: Thoracocentesis
2.2K
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
2.2K
Pneumothorax-II
1.5K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
1.5K
Development of the Lymphatic System
2.7K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.7K
Chest Physiotherapy
2.7K
Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
2.7K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
834
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
834

