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Construct Type and Risk Factors for Pseudarthrosis at the Cervicothoracic Junction
Justin S Yang1, Jacob M Buchowski, Vivek Verma
1From the Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO.
Small rods and transitional constructs showed similar pseudarthrosis rates for cervicothoracic junction stabilization. Transitional constructs, however, had higher complication rates, blood loss, and operating times.
Area of Science:
- Spine surgery
- Orthopedic surgery
- Cervicothoracic junction stabilization
Background:
- Various surgical constructs are used for cervicothoracic junction stabilization.
- Objective comparison of clinical outcomes between different constructs is lacking.
- Hypothesis: Similar fusion and complication rates for small rods versus transitional constructs.
Purpose of the Study:
- Compare clinical outcomes of small rods (3.2-mm/3.5-mm) versus transitional constructs for cervicothoracic junction stabilization.
- Identify risk factors for pseudarthrosis at the cervicothoracic junction.
Main Methods:
- Retrospective cohort study of 135 patients.
- Prospective database review with 24-month imaging follow-up.
- Univariate and multivariate analyses for construct comparison and risk factor identification.
Main Results:
- No significant difference in pseudarthrosis rates between small rods (7%) and transitional constructs (8.6%).
- Transitional constructs associated with higher complication rates (P < 0.03), increased blood loss (P < 0.001), and longer operating times (P < 0.03).
- Multivariate analysis identified tobacco use, corpectomy, lack of anterior construct, and longer construct length as pseudarthrosis risk factors.
Conclusions:
- Pseudarthrosis rates are similar between small rods and transitional constructs for cervicothoracic junction stabilization.
- Transitional constructs involve higher complication rates, blood loss, and operative time.
- Key risk factors for pseudarthrosis include tobacco use, corpectomy, anterior construct absence, and construct length.
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