Related Experiment Videos
[Hyper-HDL-cholesterolemia: prevalence and clinical aspects]
Schweizerische Medizinische Wochenschrift
|December 16, 1989
Summary
High-HDL-cholesterolemia is more common in females and often presents with a normal lipid profile. Patients with high HDL cholesterol have lower rates of obesity, diabetes, and smoking, but higher alcohol intake.
Area of Science:
- Cardiovascular Health
- Lipid Metabolism
- Clinical Medicine
Context:
- Investigated high-density lipoprotein (HDL) cholesterolemia prevalence and clinical features in 2000 outpatients.
- Analyzed data from 1215 males and 785 females aged 14-88 years.
- Examined associations with lipid profiles, obesity, diabetes, smoking, and alcohol consumption.
Purpose:
- To determine the prevalence and clinical characteristics of high-HDL-cholesterolemia.
- To compare clinical profiles of patients with high-HDL-cholesterolemia versus low-HDL-cholesterolemia.
- To explore potential contributing factors, including environmental and genetic influences.
Summary:
- High-HDL-cholesterolemia incidence was 7% in males and 9.9% in females (HDL >1.68 mmol/l and >1.94 mmol/l, respectively).
- In 80% of cases, high HDL cholesterol was associated with a normal Fredrickson lipid profile.
- Patients with high HDL cholesterol showed lower rates of obesity, hyperlipidemia, diabetes, and smoking, but higher daily alcohol intake and fewer ischemic cardiovascular events.
Impact:
- Provides insights into the clinical presentation and risk factor profile of high-HDL-cholesterolemia.
- Suggests that high HDL cholesterol may be protective against ischemic cardiovascular events.
- Highlights the complex interplay of genetic and environmental factors in high-HDL-cholesterolemia etiology.