Related Experiment Video
Updated: Apr 9, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
EvoMS: An evolutionary tool to find de novo metabolic pathways
Matias F Gerard1, Georgina Stegmayer1, Diego H Milone1
1Research Institute for Signals, Systems and Computational Intelligence (sinc(i)), FICH-UNL/CONICET, Argentina.
Abstract:
The evolutionary metabolic synthesizer (EvoMS) is an evolutionary tool capable of finding novel metabolic pathways linking several compounds through feasible reactions. It allows system biologists to explore different alternatives for relating specific metabolites, offering the possibility of indicating the initial compound or allowing the algorithm to automatically select it. Searching process can be followed graphically through several plots of the evolutionary process. Metabolic pathways found are displayed in a web browser as directed graphs. In all cases, solutions are networks of reactions that produce linear or branched metabolic pathways which are feasible from the specified set of available compounds. Source code of EvoMS is available at http://sourceforge.net/projects/sourcesinc/files/evoms/. Subsets of reactions are provided, as well as four examples for searching metabolic pathways among several compounds. Available as a web service at http://fich.unl.edu.ar/sinc/web-demo/evoms/.
Related Concept Videos
Other Glycolytic Pathways
Amino Acid Biosynthetic Pathways
Metabolism of Chemolithotrophs
Evolution of Microbial Genome
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Synthetic Biology
Golden rice
Golden rice is a genetically modified...

