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Updated: Apr 9, 2026

Author Spotlight: A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules
Published on: May 19, 2023
Combination of texture and shape features to detect pulmonary abnormalities in digital chest X-rays
Alexandros Karargyris1, Jenifer Siegelman2,3, Dimitris Tzortzis4
1Communications Engineering Branch, Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA. akarargyris@gmail.com.
Purpose:
To improve detection of pulmonary and pleural abnormalities caused by pneumonia or tuberculosis (TB) in digital chest X-rays (CXRs).
Methods:
A method was developed and tested by combining shape and texture features to classify CXRs into two categories: TB and non-TB cases. Based on observation that radiologist interpretation is typically comparative: between left and right lung fields, the algorithm uses shape features to describe the overall geometrical characteristics of the lung fields and texture features to represent image characteristics inside them.
Results:
Our algorithm was evaluated on two different datasets containing tuberculosis and pneumonia cases.
Conclusions:
Using our proposed algorithm, we were able to increase the overall performance, measured as area under the (ROC) curve (AUC) by 2.4 % over our previous work.
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