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Pancreatic pleomorphic rhabdomyosarcoma.
Ali Shirafkan Md1, Nahal Boroumand Md2, Spogmai Komak Md1
1Texas Transplant Center and Hepatobiliary Surgery, Department of Surgery, University of Texas Medical Branch, USA.
International Journal of Surgery Case Reports
|June 21, 2015
Summary
Rhabdomyosarcoma (RMS) is a rare cancer. This case highlights undifferentiated pleomorphic RMS in the pancreas and liver, emphasizing its rarity in adults and challenging diagnosis.
Area of Science:
- Oncology
- Pathology
Background:
- Rhabdomyosarcoma (RMS) is a rare malignancy originating from embryonic mesenchyme.
- RMS of the biliary tree is exceptionally uncommon, particularly in adults.
Purpose of the Study:
- To report a rare case of undifferentiated pleomorphic RMS involving the pancreas and liver in an adult.
- To discuss the diagnostic challenges and treatment of this rare condition.
Main Methods:
- A 62-year-old woman with a rapidly growing abdominal mass underwent surgical resection.
- Pathology confirmed undifferentiated pleomorphic RMS.
- The patient received chemotherapy and radiotherapy.
Main Results:
- A large pancreatic mass extending into the liver was resected.
- The patient experienced disease recurrence and died 2 years post-treatment.
- Preoperative diagnosis was challenging due to unspecific symptoms and imaging.
Conclusions:
- Pleomorphic RMS in the biliary tree is rare, primarily affecting infants and children.
- Surgical resection followed by chemotherapy and radiotherapy is the primary treatment for adult RMS.
- RMS should be considered in the differential diagnosis of atypical pancreatic and liver lesions in adults.
