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Other adverse pregnancy outcomes and future chronic disease
Justin Bohrer1, Deborah B Ehrenthal2
1Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI.
Insights
Pregnancy complications like gestational diabetes and preterm birth signal future cardiovascular disease risk in women. Recognizing these as indicators can improve early detection and women
Area of Science:
- Cardiovascular health in women
- Reproductive medicine
- Public health
Background:
- Cardiovascular disease (CVD) is a primary cause of death in women globally.
- Pregnancy induces physiological changes that can reveal underlying cardiovascular risks.
- Existing research links gestational diabetes and hypertensive disorders of pregnancy to increased future CVD risk.
Purpose of the Study:
- To highlight the significance of pregnancy complications as indicators of future cardiovascular disease risk in women.
- To advocate for the inclusion of adverse pregnancy outcomes in cardiovascular risk assessments.
- To emphasize pregnancy as a critical opportunity for early cardiovascular risk identification.
Main Methods:
- Literature review and synthesis of existing epidemiological data.
- Analysis of the association between specific pregnancy complications and long-term cardiovascular health.
- Discussion of clinical implications and integration into primary care.
Main Results:
- Women with gestational diabetes or hypertensive disorders of pregnancy face elevated long-term CVD risk.
- Emerging evidence suggests preterm birth and fetal growth restriction also correlate with increased future CVD risk.
- These pregnancy outcomes should be considered valuable cardiovascular risk indicators.
Conclusions:
- Adverse pregnancy outcomes serve as crucial markers for identifying women at heightened risk of future cardiovascular disease.
- Integrating these indicators into routine clinical practice can facilitate proactive cardiovascular risk management.
- Enhanced clinician knowledge and better integration of women's primary care are essential for effective implementation.
Abstract:
Cardiovascular disease is the leading cause of morbidity and mortality in females worldwide. Pregnancy is associated with significant physiologic changes that may function as a natural stress test to detect women at future risk. It is established that women who have had a pregnancy complicated by gestational diabetes or a hypertensive disorder of pregnancy are at increased risk of cardiovascular disease later in life, and there is growing evidence that women who deliver infants preterm or growth-restricted infants have an elevated risk as well. Consideration should be given to including these outcomes as indicators of cardiovascular risk. Pregnancy represents a teachable moment when it would be ideal to identify women at risk. Improved integration of women's primary health care and an enhanced knowledge base on the part of clinicians will be necessary to fully incorporate these findings into the clinical care of women.
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