Related Experiment Video
Updated: Apr 9, 2026

Murine Kidney Transplant Technique
Published on: October 20, 2015
Changes in Exfoliative Cell of Oral Mucosa in Kidney Transplant Patients
M Keles1, F Caglayan2, U Tozoglu3
1Department of Nephrology, Faculty of Medicine, Mevlana University, Konya, Turkey.
Objectives:
The aim of this study was to investigate quantitative cytologic changes in oral mucosal smears collected from kidney transplant patients by modern stereologic methods.
Methods:
We enrolled 32 kidney transplant patients. Smears were obtained from the buccal mucosa transplant patients before and 12 months after kidney transplantation. Smears from each individual were stained using the Papanicolaou method and were analyzed using a stereological method.
Results:
Statistically, the nuclear volumes and cytoplasmic volumes in the cells of buccal mucosa were markedly higher after kidney transplantation (P < .05). There was a decreased positive cell density in the oral epithelial cells after kidney transplantation compared with before renal transplantation (P < .05).
Conclusions:
These findings suggest that there are alterations in the oral epithelial cells after kidney transplantation, which are detectable by microscopy and cytomorphometry.
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