The surprising temporal specificity of direct-current stimulation
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Updated: Apr 9, 2026
Transcranial Direct Current Stimulation and Simultaneous Functional Magnetic Resonance Imaging
Published on: April 27, 2014
Robert M G Reinhart1, Geoffrey F Woodman1
1Department of Psychology, Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center, Vanderbilt University, Nashville, TN 37240, USA.
Abstract:
As studies increasingly use transcranial direct-current stimulation (tDCS) to manipulate brain activity, surprising results are emerging. Specifically, research combining tDCS with electrophysiology is showing that the long-lasting effects of tDCS can counter-intuitively influence specific neural mechanisms active for as little as 100 ms during the flow of human information processing.
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