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Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression
Published on: January 19, 2019
[Hemostasis and T-cell immunity in lung cancer patients]
Abstract:
Complex examination of hemostatic system and T-cell-mediated immunity in 19 cases of stage II-IV lung cancer showed an increased activity of blood coagulation system to be associated with a decrease in OKT3+, OKT11+ and OKT4+ T-lymphocyte subsets levels. A reverse correlation was established between plasma--Willebrand's factor level and those of OKTè+ and OKT8+ lymphocytes whereas a direct one--between blood-platelet aggregate level and that of OKT4+. The data obtained emphasized the need to consider the status of hemostatic system when evaluating the function of cell-mediated immunity.
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