Related Experiment Video

Updated: Apr 9, 2026

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
05:36

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

8.7K

Time on the scene and interventions are associated with improved survival in pediatric out-of-hospital cardiac arrest

Janice A Tijssen1, David K Prince2, Laurie J Morrison3

  • 1Division of Pediatric Critical Care Medicine, Department of Pediatrics, London Health Sciences Centre, University of Western Ontario, London, ON, Canada; The Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada.

Resuscitation
|June 23, 2015
PubMed

Insights

Optimal scene time for pediatric out-of-hospital cardiac arrest survival is 10-35 minutes. Fluid resuscitation improved survival, while advanced airway and resuscitation drugs did not enhance outcomes.

Area of Science:

  • Pediatric Emergency Medicine
  • Cardiovascular Research
  • Public Health

Background:

  • Pediatric out-of-hospital cardiac arrest (OHCA) has a survival rate below 10%.
  • The impact of on-scene time and advanced life support (ALS) interventions on pediatric OHCA survival is not well understood.

Purpose of the Study:

  • To determine the association between on-scene time and survival in pediatric OHCA patients.
  • To identify specific prehospital interventions linked to improved survival rates.

Main Methods:

  • Analysis of the Resuscitation Outcomes Consortium cardiac arrest database (2005-2012).
  • Inclusion of 2244 pediatric patients (3 days to 19 years) with OHCA across 11 North American regions.
  • Evaluation of survival to hospital discharge based on on-scene times (<10, 10-35, >35 minutes) and interventions.

Main Results:

  • Infants had the lowest survival (3.7%), while adolescents had the highest (16.3%).
  • Survival was highest with 10-35 minutes on-scene time (10.2%) compared to <10 minutes (5.3%) or >35 minutes (6.9%).
  • Intravenous/intra-osseous access and fluid administration correlated with improved survival; advanced airway attempts and resuscitation drugs did not.

Conclusions:

  • A scene time of 10-35 minutes was associated with the highest survival rates in pediatric OHCA, particularly for adolescents.
  • Fluid resuscitation was linked to better survival, whereas advanced airway procedures and resuscitation drugs showed no benefit or potential harm.
Abstract

Keywords:
Cardiac arrestEmergency medical servicesPediatric

More Related Videos

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

3.2K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.5K

Related Concept Videos

Cardiopulmonary Resuscitation I: Adult01:21

Cardiopulmonary Resuscitation I: Adult

Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...
1.1K
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
1.4K
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
1.4K
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
478
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
1.0K
Introduction Cardiac Emergencies01:30

Introduction Cardiac Emergencies

Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
510