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Related Concept Videos

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Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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Related Experiment Video

Updated: Apr 8, 2026

Generation and On-Demand Initiation of Acute Ictal Activity in Rodent and Human Tissue
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Early seizures in acute stroke.

Chraa Mohamed1, Najib Kissani1

  • 1Neurology Department, Mohamed VI University Hospital, Marrakesh, Morocco.

The Pan African Medical Journal
|June 23, 2015
PubMed
Summary
This summary is machine-generated.

Early seizures (ES) occurred in 13% of first-ever stroke patients. Cortical involvement and hemorrhagic transformation predicted ES, which were linked to worse outcomes like mortality and disability.

Keywords:
Ischemic strokeearly seizuresprognosisrisk factors

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Area of Science:

  • Neurology
  • Stroke Medicine
  • Epileptology

Background:

  • Early seizures (ES) are a potential complication following acute stroke.
  • Understanding the frequency and predictors of ES is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of early seizures in patients experiencing their first-ever stroke.
  • To identify factors predicting early seizures.
  • To evaluate the clinical outcomes associated with early seizures.

Main Methods:

  • Retrospective study of 352 consecutive patients with first-ever stroke.
  • Exclusion of patients with a prior epilepsy history.
  • Definition of early seizures as occurring within 7 days of stroke onset.

Main Results:

  • 13% of patients (47/352) experienced early seizures; 8 had status epilepticus.
  • Early seizures were more frequent in cases with cortical involvement, severe/large strokes, and cortical hemorrhage.
  • Hemorrhagic transformation was identified as a predictive factor for ES.
  • Early seizures correlated with increased adverse outcomes, including mortality and disability.

Conclusions:

  • Early seizures affect approximately 13% of first-ever stroke patients.
  • Predictive factors for ES include cortical involvement and hemorrhagic transformation.
  • Early seizures are associated with poorer clinical outcomes after acute stroke.