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The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse
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The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse

Published on: July 25, 2011

[Therapy of cerebral infarction by infusion of plasma substitutes]

F I Vasilenko

    Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
    |January 1, 1989
    PubMed

    In a total of 152 cases of severe cerebral infarction intravascular infusion of plasma substitutes was a part of combined therapy. Hemostasis studies in these patients allowed us to detect various degrees of hypercoagulation as a response to hemodilution. In cases of most pronounced post-hemodilution++ hypercoagulation (77 patients) complications, including those of thrombohemorrhagic nature, were increased in rate (74%) with more severe course of cerebral infarction. Of these 77 patients 46 died (59.7%). In 75 cases with no substantial hypercoagulation, the disease had a more benign course with 2 casulties (2.7%). The hemodilution tests should precede the therapeutic use of plasma substitutes in cerebral infarct patients.

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