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Updated: Apr 8, 2026

An “All-laser” Endothelial Transplant
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Evolving Techniques in Corneal Transplantation.

Grace E Boynton1, Maria A Woodward1

  • 1Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Kellogg Eye Center, 1000 Wall St., Ann Arbor, MI 48105, USA.

Current Surgery Reports
|June 24, 2015
PubMed
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Corneal transplantation restores vision by replacing damaged corneas. Modern partial-thickness techniques are increasingly preferred over traditional full-thickness penetrating keratoplasty (PKP) for better outcomes.

Area of Science:

  • Ophthalmology
  • Transplant Surgery

Background:

  • Corneal transplantation is a common procedure to restore vision in patients with corneal diseases.
  • Penetrating keratoplasty (PKP), the traditional full-thickness corneal transplant, has been the standard surgical approach.
  • Advancements have led to the development of partial-thickness techniques.

Purpose of the Study:

  • To review current surgical techniques in corneal transplantation.
  • To emphasize indications for corneal transplant procedures.
  • To discuss postoperative outcomes of different corneal transplant methods.

Main Methods:

  • Review of current literature on corneal transplantation techniques.
  • Focus on penetrating keratoplasty (PKP) and newer partial-thickness procedures.
Keywords:
Corneal transplantationDeep anterior lamellar keratoplastyDescemet membrane endothelial keratoplastyDescemet stripping endothelial keratoplastyPenetrating keratoplasty

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  • Analysis of indications and outcomes for each technique.

    • Main Results:

    • A shift from PKP towards partial-thickness corneal transplantation is observed.
    • Partial-thickness techniques selectively replace diseased corneal layers, preserving healthy tissue.
    • These newer methods offer potential advantages in postoperative outcomes.

    Conclusions:

    • Partial-thickness corneal transplantation techniques are gaining prominence.
    • Selective tissue replacement in lamellar keratoplasty improves outcomes.
    • The review highlights evolving surgical strategies and their impact on vision restoration.