Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

773
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
773
Hormonal Regulation01:33

Hormonal Regulation

37.2K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
37.2K
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

1.2K
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Circulating neutrophil extracellular traps and deoxyribonuclease in gestational diabetes mellitus.

Journal of reproductive immunology·2026
Same author

Oscillometric blood pressure values in infants at 3, 6 and 12 months of age: a cohort study.

BMJ paediatrics open·2026
Same author

Maternal Body Mass Index, Offspring Impaired Skin Barrier Function, Allergic Sensitization, and Bronchial Obstruction.

Allergy·2026
Same author

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke·2026
Same author

Co-creation of a mobile health program (MumCare) for preventing maternal cardiovascular disease after pregnancy complications.

Frontiers in global women's health·2026
Same author

A new treatment for preterm pre-eclampsia could benefit mother and child.

Nature medicine·2026

Related Experiment Video

Updated: Apr 8, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.5K

Circulating predictive biomarkers in preeclampsia.

Anne Cathrine Staff1

  • 1Department of Obstetrics and Gynaecology, Oslo University Hospital, Ulleval, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway.

Pregnancy Hypertension
|June 25, 2015
PubMed
Summary
This summary is machine-generated.

Researchers reviewed biomarkers for predicting preeclampsia. While angiogenic factors show promise, current prediction biomarker tests lack the necessary accuracy for widespread screening, though they can aid research and high-risk patient selection.

More Related Videos

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
12:17

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo

Published on: August 2, 2017

11.4K
A Plate-based Cytotoxicity Assay for the Assessment of Rat Placental Natural Killer Cell Cytolytic Function
10:44

A Plate-based Cytotoxicity Assay for the Assessment of Rat Placental Natural Killer Cell Cytolytic Function

Published on: June 2, 2019

6.4K

Related Experiment Videos

Last Updated: Apr 8, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.5K
The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
12:17

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo

Published on: August 2, 2017

11.4K
A Plate-based Cytotoxicity Assay for the Assessment of Rat Placental Natural Killer Cell Cytolytic Function
10:44

A Plate-based Cytotoxicity Assay for the Assessment of Rat Placental Natural Killer Cell Cytolytic Function

Published on: June 2, 2019

6.4K

Area of Science:

  • Obstetrics and Gynecology
  • Biomarker Research
  • Maternal-Fetal Medicine

Background:

  • Preeclampsia poses significant risks to maternal and fetal health.
  • Accurate prediction biomarkers are crucial for early intervention and improved outcomes.
  • Current diagnostic methods for preeclampsia have limitations.

Purpose of the Study:

  • To review and evaluate promising prediction biomarkers for preeclampsia.
  • To assess the current state of blood-based biomarker research for preeclampsia prediction.
  • To determine the clinical utility of identified biomarkers in screening and management.

Main Methods:

  • Systematic review of PubMed abstracts using keywords: "preeclampsia", "biomarker", "prediction".
  • In-depth review of primary research papers focusing on blood-based biomarkers.
  • Analysis of predictive test values, sensitivity, and specificity of identified biomarkers.

Main Results:

  • Angiogenic factors (PlGF, sFlt-1) and PP13 demonstrate potential as preeclampsia prediction biomarkers.
  • Current biomarkers exhibit insufficient sensitivity and specificity for population-level screening.
  • Biomarker testing is recommended within research protocols.

Conclusions:

  • Biomarkers show potential for identifying high-risk pregnancies for targeted interventions.
  • Further research is needed to enhance biomarker accuracy and clinical applicability.
  • Biomarkers can aid in selecting participants for prophylactic trials and guiding closer pregnancy monitoring.